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|SAN FRANCISCO Vladimir Sobotka Blues Jersey , Aug. 25 (Xinhua) -- Researchers at Oregon State University (OSU) have found the bacterial communities that live inside everyone are quite similar and stable when times are good, but when stress enters the equation, those communities can react very differently from person to person.
Published this week in Nature Microbiology and referred to as a microbiological version of the "Anna Karenina principle," the new paradigm gets its name from the opening line of the novel "Anna Karenina" by 19th century Russian author Leo Tolstoy: "All happy families are alike; each unhappy family is unhappy in its own way."
"When microbiologists have looked at how microbiomes change when their hosts are stressed from any number of factors - temperature, smoking Colton Parayko Blues Jersey , diabetes, for example - they've tended to assume directional and predictive changes in the community," explained Rebecca Vega Thurber, an assistant professor at OSU and corresponding author on the study.
However, Vega Thurber noted in a news release Carter Hutton Blues Jersey , "after tracking many datasets of our own we never seemed to find this pattern but rather a distinct one where microbiomes actually change in a stochastic, or random, way."
By surveying the literature on microbial changes caused by perturbation, lead author Jesse Zaneveld of the University of Washington-Bothell, Vega Thurber and her student Ryan McMinds at OSU found those stochastic changes to be a common occurrence.
The findings Jake Allen Blues Jersey , Vega Thurber said, indicate that "when microbiomes are happy they are all similar in their composition but during stress or unhappiness they change in a multitude of distinct ways... We think this is an important emerging paradigm for thinking about microbiome data."
Similarly, in humans, when healthy our microbiomes look alike, "but when stressed each one of us has our own microbial snowflake Kyle Brodziak Blues Jersey ," she said. "You or I could be put under the same stress, and our microbiomes will respond in different ways - that's a very important facet to consider for managing approaches to personalized medicine. Stressors like antibiotics or diabetes can cause different people's microbiomes to react in very different ways."
Humans and animals are filled with symbiotic communities of microorganisms that often fill key roles in normal physiological function and influence susceptibility to disease.
Studies of microbiome dynamics have typically looked for patterns that shift microbiomes from a healthy stable state to a dysbiotic stable state; dysbiosis refers to the microbial communities being out of their natural balance, which can result in the interruption of basic biological functions for the host person or animal.
The researchers believe their new paradigm has key implications for a more personalized approach to antibiotic therapy, management of chronic diseases and other aspects of medical care.
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Qiandaohu Lake in China's Zhejiang under stricter protection
BEIJING， May 11 (Xinhua) -- China's meteorological authority issued a blue alert on Wednesday evening， as rainstorms are expected in the country's north and southwest.
Thunderstorms and strong wind are forecast to hit parts of Hebei， Liaoning， Beijing， Shanxi and Shaanxi from Wednesday night to Thursday morning， according to a statement posted on the website of the National Meteorological Center.
Parts of Guizhou， Sichuan， Gansu and Hainan provinces will face rainstorms over the next 24 hours， with precipitation up to 40 millimeters in some parts， the statement said.
The center suggested people reduce outdoor activities during the rainy days and take precautions against mud-rock flows， mountain floods and landslides.
China has a four-tier color-coded system for severe weather， with red being the most serious， followed by orange， yellow and blue. Enditem
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